What is Freeze-Fracture Electron Microscopy?

What is Freeze-Fracture Electron Microscopy?

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A thorough comprehension of cellular bio-functionality necessitates knowledge about specific constituents of the cell membrane and, as a result, the structure and organization of protein complexes, as well as tools for high-resolution investigations.

Fundamental Technical Elements of Freeze-fracture/Freeze-etch in Biological Electron Microscopy

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Freeze fracture view of nuclear pores - Stock Image - C005/8072 - Science Photo Library

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Figure 3 from Freeze-fracture replica electron microscopy combined with SDS digestion for cytochemical labeling of integral membrane proteins. Application to the immunogold labeling of intercellular junctional complexes.